We study ion translocating mechanisms (channels, exchangers and pumps) in health and disease. Our main focus is the KATP channel, which is responsible for metabolo-electrical coupling (the coupling of intracellular energy metabolism to membrane excitability and secretion). Using genetically engineered mouse models, we investigate the roles of roles for this channel in cardioprotection and the regulation of blood flow. We also pursue molecular studies to investigate regulation of channel function and trafficking by associated proteins.
NIH Funding Opportunities
- Notice of Special Interest: Availability of Administrative Supplements to NIH Science Education Partnership Awards (SEPA) to Fund Participation in the NIH Pavilion at the 2020 USA Science and Engineering Festival (USASEF)
- Notice of NIEHS Participation in PAR-20-040 "Support of Competitive Research (SCORE) Pilot Project Award (SC2 Clinical Trial Not Allowed)"
- Notice of Extension of expiration date for PA-17-100 HIV infection of the Central Nervous System (R01)
- Notice of Extension of the Expiration Date in PAR-18-630, Investigator Initiated Extended Clinical Trial (R01 Clinical Trial Required)
- Notice of Change to Application Due Date for RFA-CA-20-003 "Limited Competition: Biospecimen Bank to Support NCI Early-Phase and Experimental Clinical Trials (U24 Clinical Trials Not Allowed)"