We study ion translocating mechanisms (channels, exchangers and pumps) in health and disease. Our main focus is the KATP channel, which is responsible for metabolo-electrical coupling (the coupling of intracellular energy metabolism to membrane excitability and secretion). Using genetically engineered mouse models, we investigate the roles of roles for this channel in cardioprotection and the regulation of blood flow. We also pursue molecular studies to investigate regulation of channel function and trafficking by associated proteins.
NIH Funding Opportunities
- Pre-Application Webinar for Population-Based Researchers on NCI's Informatics Technologies for Cancer Research Funding Opportunities (RFA-CA-19-038, RFA-CA-19-039, RFA-CA-19-040, and RFA-CA-19-041)
- Notice to Extend the Expiration Date of PAR-18-291: Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Clinical Trial Not Allowed)
- Notice to Extend the Expiration Date of PAR-18-261: Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Clinical Trial Required)
- Notice of Correction to Eligibility Information for PA-19-166 "Implementation of shared decision making for HLBS diseases and conditions (R01 Clinical Trial Optional)"
- Notice of Change to Key Dates for RFA-NS-18-014 "BRAIN Initiative: Targeted BRAIN Circuits Planning Projects - TargetedBCPP (R34 Clinical Trial Not Allowed)"