We study ion translocating mechanisms (channels, exchangers and pumps) in health and disease. Our main focus is the KATP channel, which is responsible for metabolo-electrical coupling (the coupling of intracellular energy metabolism to membrane excitability and secretion). Using genetically engineered mouse models, we investigate the roles of roles for this channel in cardioprotection and the regulation of blood flow. We also pursue molecular studies to investigate regulation of channel function and trafficking by associated proteins.
NIH Funding Opportunities
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
- National Research Mentoring Network: The Science of Mentoring, Networking, and Navigating Career Transition Points (U01 Clinical Trial Not Allowed)
- National Research Mentoring Network (NRMN) Resource Center (U24 - Clinical Trial Not Allowed)
- National Research Mentoring Network (NRMN) Coordination Center (U24 - Clinical Trial Not Allowed)