NIH Funding Opportunities

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Fri, 02/16/2018 - 12:48
Funding Opportunity PA-18-671 from the NIH Guide for Grants and Contracts. The purpose of the Kirschstein-NRSA predoctoral fellowship (F31) award is to enable promising predoctoral students to obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training must reflect the applicants dissertation research project and is expected to clearly enhance the individuals potential to develop into a productive, independent research scientist. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Fri, 02/16/2018 - 12:28
Funding Opportunity PA-18-668 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support students at institutions with NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g. DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD), and who intend careers as physician/clinician-scientists. Applicants must propose an integrated research and clinical training plan and a dissertation research project in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The fellowship experience is expected to clearly enhance the individual's potential to develop into a productive, independent physician/clinician-scientist. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor
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National Research Mentoring Network: The Science of Mentoring, Networking, and Navigating Career Transition Points (U01 Clinical Trial Not Allowed)

Fri, 02/16/2018 - 11:09
Funding Opportunity RFA-RM-18-004 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for the second phase of the NIH National Research Mentoring Network (NRMN) efforts. The NRMN is a nationwide consortium that was designed to enhance mentoring and career development of individuals from groups underrepresented in the biomedical research workforce. This new cycle of NRMN will expand the scientific scope of the program to encourage grants with varied approaches aimed at the science of mentorship, networking, and navigating critical career transition points. The NRMN will be a set of cooperative agreements in which the Program Directors/Principal Investigators (PDs/PIs) will work through a NRMN Coordination Center and the NRMN Resource Center to disseminate effective resources. The NRMN research is expected to align with the hallmarks of success that have been defined by the Diversity Program Consortium and the Center for Evaluation and Coordination (CEC).
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National Research Mentoring Network (NRMN) Resource Center (U24 - Clinical Trial Not Allowed)

Fri, 02/16/2018 - 11:09
Funding Opportunity RFA-RM-18-002 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications from qualified institutions for the NIH National Research Mentoring Network (NRMN) Resource Center. The NRMN is a nationwide consortium intended to enhance the training and career development of biomedical researchers from diverse backgrounds, through enhanced networking and mentorship experiences. One grant will be awarded for the development and management of a NRMN Resource Center, which will provide a web-based mentoring tool to facilitate real-time mentor/mentee engagement and networking. The awardee will also oversee the management of the NRMN website, report on outputs from NRMN components, and serve as a repository for publicly available mentoring resources and tools.
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National Research Mentoring Network (NRMN) Coordination Center (U24 - Clinical Trial Not Allowed)

Fri, 02/16/2018 - 11:09
Funding Opportunity RFA-RM-18-003 from the NIH Guide for Grants and Contracts. The National Research Mentoring Network (NRMN) is a nationwide consortium developed to enhance the training and career development of individuals from diverse backgrounds who are pursuing biomedical research careers by providing networking and mentorship experiences. The NRMN Coordination Center will provide infrastructure and expertise that supports the collection, secure storage, and reporting of data generated by the individual NRMN component projects. Building upon the instruments and processes developed to assess the impact of NRMN activities in the previous Diversity Program Consortium (DPC) funding period, the NRMN Coordination Center will coordinate the early stages of collection of data in an ongoing way, and provide feedback to the consortium to maximize the research benefit of the various NRMN activities. The NRMN Coordination Center will also be responsible for promoting synergistic interactions with the DPC Center for Evaluation and Coordination (CEC) for the long-term collection and storage of data.
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Broad Agency Announcement: Immune Mechanisms of Protection Against Mycobacterium tuberculosis Center (IMPAc-TB) NIAID-DAIT-NIHAI201700104

Fri, 02/16/2018 - 01:21
Notice NOT-AI-18-019 from the NIH Guide for Grants and Contracts
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Fri, 02/16/2018 - 01:18
Funding Opportunity PA-18-670 from the NIH Guide for Grants and Contracts. The purpose of the Kirschstein-NRSA postdoctoral fellowship is to support research training of highly promising postdoctoral candidates who have the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of the participating NIH Institutes and Centers. Applications are expected to incorporate exceptional mentorship. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
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Broad Agency Announcement: Vaccine Adjuvant Discovery Program NIAID-DAIT-NIHAI201700100

Thu, 02/15/2018 - 12:43
Notice NOT-AI-18-018 from the NIH Guide for Grants and Contracts
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Notice of National Institute of Neurological Disorders and Stroke (NINDS) Interest in Biomarkers Directed at Pain or Pain Therapies

Thu, 02/15/2018 - 12:37
Notice NOT-NS-18-043 from the NIH Guide for Grants and Contracts
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Notice of NINR involvement in RFA-TW-17-001 Health-Professional Education Partnership Initiative (HEPI) (R25 - Clinical Trial Not Allowed)

Thu, 02/15/2018 - 12:03
Notice NOT-NR-18-008 from the NIH Guide for Grants and Contracts
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Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (T1D) (R01 Clinical Trial Optional)

Thu, 02/15/2018 - 11:58
Funding Opportunity RFA-DK-18-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective cell replacement therapies for type 1 diabetes (T1D). The purpose is to support research leading to the development and testing of novel and supportive technologies for the improvement of cell replacement interventions using novel biomaterials and devices for T1D treatment.
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National Laboratory Curriculum Framework Development

Thu, 02/15/2018 - 11:38
Funding Opportunity RFA-FD-18-005 from the NIH Guide for Grants and Contracts. The Food and Drug Administration (FDA), Office of Regulatory Affairs (ORA), Office of Training Education and Development (OTED) is announcing this Funding Opportunity Announcement (FOA) for a Cooperative Agreement Grant. The goals of this Cooperative Agreement Grant are to continue the development of the Integrated Food Safety System (IFSS) National Curriculum Standard (NCS) for the laboratory competency and curriculum frameworks, further work on the development and validation of competency statements. As the NCS is completed at each level, then training content can be developed to meet the standard, post web courses and deliver classroom courses to IFSS laboratorians nationwide. Under FSMA Section 209, FDA is directed to improve the training of state, local, territorial and tribal food safety officials and set standards and administer training and education programs to ensure a competent work force doing comparable work.
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NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

Thu, 02/15/2018 - 11:32
Funding Opportunity PAR-18-665 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) applications from small business concerns (SBCs) that seek additional funding to support clinical trials for projects that were previously funded by NIH SBIR and STTR Phase II awards. The projects must focus on products related to the mission and goals of the National Institute of Neurological Disorders and Stroke (NINDS) and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Since conducting the clinical trials needed for commercialization may be capital-intensive, the FOA aims to facilitate the transition of SBIR Phase II projects to the commercialization stage by promoting partnerships between NIHs SBIR/STTR awardees and third-party investors and/or strategic partners. Consistent with the goals of this funding initiative and as required by the SF424 instructions for all SBIR Phase II applications, applicants must submit a Commercialization Plan, which should include details on any independent third-party investor funding that has already been secured or is anticipated during the project period. It is expected that the level of this independent third-party funding will equal or exceed the NINDS funds being requested throughout the SBIR Phase IIB project period.
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31)

Thu, 02/15/2018 - 11:32
Funding Opportunity PA-18-666 from the NIH Guide for Grants and Contracts. The purpose of this Kirschstein-NRSA predoctoral fellowship (F31) award is to enhance the diversity of the health-related research workforce by supporting the research training of predoctoral students from population groups that have been shown to be underrepresented in the biomedical, behavioral, or clinical research workforce, including underrepresented racial and ethnic groups and those with disabilities. Through this award program, promising predoctoral students will obtain individualized, mentored research training from outstanding faculty sponsors while conducting well-defined research projects in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training is expected to clearly enhance the individuals potential to develop into a productive, independent research scientist
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Impact of the Use of Glucose Monitoring and Control Technologies on Health Outcomes and Quality of Life in Older Adults with Type 1 Diabetes (T1D) (R01 Clinical Trial Required)

Thu, 02/15/2018 - 10:50
Funding Opportunity RFA-DK-17-024 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing clinical studies of the use of current and emerging technologies for monitoring of blood glucose and insulin administration in older adults. (aged 65 years or older) Older adults may have increased vulnerability to hypoglycemia, cognitive impairment and/or multiple co-morbidities which may affect the risks and benefits of these technologies in this population. This research is intended to improve health, glucose control and quality of life of older patients with type 1 diabetes Only human studies will be considered responsive to this FOA; applications involving animal or invitro studies are not responsive to this FOA.
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Clinical, Behavioral and Physiological Research Testing Current and Novel Closed Loop Systems (R01- Clinical Trial Required)

Thu, 02/15/2018 - 10:50
Funding Opportunity RFA-DK-17-023 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing clinical trials to test a highly reliable, wearable/implantable, portable, and easy to operate system linking continuous glucose monitoring and pancreatic hormone delivery in a closed loop system. This research is also intended to study behavioral and physiological aspects of relevance to the use and adoption of these systems. The main goal of this FOA is to improve glucose control and quality of life of patients with type 1 diabetes. Only human studies will be considered responsive to this FOA, applications involving animal or in vitro studies are not responsive to this FOA.
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Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R01- Clinical Trial Optional)

Thu, 02/15/2018 - 10:50
Funding Opportunity RFA-DK-17-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective open- and closed-loop glucose control systems. Proposed research should tackle important obstacles at the level of sensing, hormone formulation and delivery, self-management decision support systems, and/or design of automated controllers/algorithms able to manage an integrated platform. This research may contribute to development of affordable and user friendly technologies to improve glucose control in patients with type 1 diabetes.
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Extending Deadline for RFA-FD-18-004

Thu, 02/15/2018 - 10:48
Notice NOT-FD-18-005 from the NIH Guide for Grants and Contracts
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Exploiting Omics Assays to Investigate Molecular Regulation of Persistent HIV in Individuals with Substance Use Disorder (R61/R33 Clinical Trial Optional)

Thu, 02/15/2018 - 10:27
Funding Opportunity RFA-DA-19-003 from the NIH Guide for Grants and Contracts. This initiative will support projects that exploit Omics assays to address outstanding questions regarding molecular regulation of persistent HIV (e.g. latency or reservoirs) in the context of chronic substance use or substance use disorder (SUD).
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The Characterization and Discovery of Novel Autoantigens and Epitopes in Type 1 Diabetes (R01 Clinical Trial Optional)

Thu, 02/15/2018 - 10:18
Funding Opportunity RFA-DK-17-031 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research aimed at the characterization and discovery of neoantigens and neoepitopes in type 1 diabetes. These include the characterization of the humoral and cell mediated autoimmune responses elicited by these neoepitopes and neoantigens and their role in the etiology and pathophysiology of type 1 diabetes. These studies should be integrated with the present knowledge of established epitopes and antigens (e.g. autoantibodies for insulin, GAD65, IA-2, and ZnT8T).
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